In 2014 wurden an den Kassamärkten der Deutschen Börse 1,28 Bio. Euro umgesetzt (2013: 1,16 Bio. Euro).
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Jenaer Forscher des Leibniz-Instituts für Altersforschung fanden nun heraus, dass das Wilms-Tumor-Gen WT1 eine Schlüsselposition in einem komplexen Netzwerk…
Das Bundesministerium für Bildung und Forschung (BMBF) hat am 1. Januar 2015 die Erprobung eines Telefonservice zur Weiterbildungsberatung begonnen.
In einem 6-monatigen Programm werden interdisziplinäre Teams ab Februar 2015 bei der Umsetzung und dem Wachstum ihrer Gründungsvorhaben unterstützt. Sie können…
Mithilfe von Gold-Nanopartikeln kann ein von den Krebszellen erzeugtes Enzym erkannt und dessen Zerstörung bewirkt werden. Das haben Forscher des zum…
The present invention relates to a process for the photolithographic biochip synthesis in which photolabile protective groups of the 2-(2-nitrophenyl) ethyl type are used, wherein the irradiation step common for the photolithographic chip synthesis is carried out in the presence of base, preferably a non-nucleophilic base.
The present technology provides 3'-photolabile nucleoside derivatives for producing nucleotides. The resulting oligonucleotides built up on the support by light-controlled synthesis are linked to the solid phase via the 5' end and thus can be used for investigating reactions that require free 3'-OH ends, for example certain DNA-enzyme interactions.
New method for producing a highly diverse antibody library, where pro-teins/antibodies can be selected for specific applications. A large and, compared from cell to cell, highly uniform number of antibodies is covalently attached to the surface of a eukaryotic cell. Using this technology, specific antibodies can be selected together with the presenting cell out of a high number of cells in a comparatively easy way. The technology can also be used humanizing a hybridoma cell line by enabling the homologous recombination of the constant do-mains of human immunoglobulins with the respective gene.
Optical fluorescence and gamma-labeled radio-pharmaceutical imaging offer complementary ways of probing and assessing the physiology of small animals. With the increasing use of both methods for functional molecular imaging in small animal models for applications such as cancer research and drug development, it has become more important to integrate their results, particularly for studies of the same animal. This can be performed through image registration of separate studies or through simultaneous tomographic acquisition with implicit registration of the two imaging modalities. DKFZ developed an optical imaging detector for fluorescence and bioluminescence in small animal imaging, which is compatible for single-photon emission computed tomography (SPECT).
This invention describes a simple and robust navigation aid for physicians in bronchoscopy or similar interventional surgery (angiography; implanting of vessel stents as well as cardiac pacemaker). The interventional device can be monitored and in real time and at a defined localized spot a biopsy can be taken. It improves accuracy also in the case of movement of the organ structures in opposite to established procedures. A prototype phantom has been tested successfully at the DKFZ together with the software.
DKFZ developed an optical imaging detector for fluorescence and bioluminescence in small animal imaging, which is compatible for positron electron tomography (PET). Compatibility of light detection with PET has been accomplished by developing an optical detector that consists of a 25 mm x 100 mm photon sensor (liquid cooled) for light detection, a microlens array for field-of-view definition, a septum masks for cross-talk suppression, and a transferable filter for wavelength selection.
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