Forum für Wissenschaft, Industrie und Wirtschaft

Hauptsponsoren:     3M 
Datenbankrecherche:

 

Artificial atoms allow for magnetic resonance on individual cells

12.02.2013
Scientists at ICFO develop a technique for MRIs on a molecular scale

Researchers from the Institute of Photonic Sciences (ICFO), in collaboration with the CSIC and Macquarie University in Australia, have developed a new technique, similar to the MRI but with a much higher resolution and sensitivity, which has the ability to scan individual cells.

In an article published in Nature Nanotech, and highlighted by Nature, ICFO Prof. Romain Quidant explains how this was accomplished using artificial atoms, diamond nanoparticles doped with nitrogen impurity, to probe very weak magnetic fields such as those generated in some biological molecules.

The conventional MRI registers the magnetic fields of atomic nuclei in our bodies which have been previously excited by an external electromagnetic field. The collective response of all of these atoms makes it possible to diagnose and monitor the evolution of certain diseases. However, this conventional technique has a diagnostic resolution on a millimetric scale. Smaller objects do not give enough signal to be measured.

The innovative technique proposed by the group led by Dr. Quidant significantly improves the resolution at the nanometer scale (nearly one million times smaller than the millimeter), making it possible to measure very weak magnetic fields, such as those created by proteins. "Our approach opens the door for the performance of magnetic resonances on isolated cells which will offer new sources of information and allow us to better understand the intracellular processes, enabling noninvasive diagnosis," explains Michael Geiselmann, ICFO researcher who conducted the experiment. Until now, it has only been possible to reach this resolution in the laboratory, using individual atoms at temperatures close to the absolute zero (approx. -273 degrees Celsius.)

Individual atoms are structures that are highly sensitive to their environment, with a great ability to detect nearby electromagnetic fields. The challenge these atoms present is that they are so small and volatile that in order to be manipulated, they must be cooled to temperatures near the absolute zero. This complex process requires an environment that is so restrictive that it makes individual atoms unviable for potential medical applications. Artificial atoms used by Quidant and his team are formed by a nitrogen impurity captured within a small diamond crystal. "This impurity has the same sensitivity as an individual atom but is very stable at room temperature due to its encapsulation. This diamond shell allows us to handle the nitrogen impurity in a biological environment and, therefore, enables us to scan cells" argues Dr. Quidant.

To trap and manipulate these artificial atoms, researchers use laser light. The laser works like tweezers, leading the atoms above the surface of the object to study and extract information from its tiny magnetic fields.

The emergence of this new technique could revolutionize the field of medical imaging, allowing for substantially higher sensitivity in clinical analysis, an improved capacity for early detection of diseases, and thus a higher probability for successful treatment.

This research has been possible thanks to the support of the private foundation Cellex Barcelona.

ABOUT ICFO

ICFO-The Institute of Photonic Sciences was created in 2002 by the government of Catalonia and the Technical University of Catalonia. ICFO is a center of research excellence devoted to the sciences and technologies of light with a triple mission: to conduct frontier research, train the next generation of scientists and technologists, and provide knowledge and technology transfer. As part of ICFO's goal to usher advances "made at ICFO" into society, the institute actively promotes the creation of spin-off companies by ICFO researchers.

Research at ICFO targets the forefront of science and technology based on light with programs directed at applications in Health, Renewable Energies, Information Technologies, Security and Industrial processes, among others. The center currently hosts more than 250 researchers and PhD students working in more than 60 different laboratories. All research groups and facilities are located in a dedicated 14.000 m2 building situated in the Mediterranean Technology Park in the metropolitan area of Barcelona.

ICFO researchers publish in the most prestigious journals and collaborate with a wide range of companies around the world. In recognition of research excellence, ICFO has been awarded the elite Severo Ochoa distinction by the Government of Spain. Foundation Cellex finances the NEST program at ICFO which makes possible many ambitious frontier research projects.

Albert Mundet | EurekAlert!
Further information:
http://www.icfo.eu

More articles from Physics and Astronomy:

nachricht A 100-year-old physics problem has been solved at EPFL
23.06.2017 | Ecole Polytechnique Fédérale de Lausanne

nachricht Quantum thermometer or optical refrigerator?
23.06.2017 | National Institute of Standards and Technology (NIST)

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Klima-Satellit: Mit robuster Lasertechnik Methan auf der Spur

Hitzewellen in der Arktis, längere Vegetationsperioden in Europa, schwere Überschwemmungen in Westafrika – mit Hilfe des deutsch-französischen Satelliten MERLIN wollen Wissenschaftler ab 2021 die Emissionen des Treibhausgases Methan auf der Erde erforschen. Möglich macht das ein neues robustes Lasersystem des Fraunhofer-Instituts für Lasertechnologie ILT in Aachen, das eine bisher unerreichte Messgenauigkeit erzielt.

Methan entsteht unter anderem bei Fäulnisprozessen. Es ist 25-mal wirksamer als das klimaschädliche Kohlendioxid, kommt in der Erdatmosphäre aber lange nicht...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: Die Schweiz in Pole-Position in der neuen ESA-Mission

Die Europäische Weltraumagentur ESA gab heute grünes Licht für die industrielle Produktion von PLATO, der grössten europäischen wissenschaftlichen Mission zu Exoplaneten. Partner dieser Mission sind die Universitäten Bern und Genf.

Die Europäische Weltraumagentur ESA lanciert heute PLATO (PLAnetary Transits and Oscillation of stars), die grösste europäische wissenschaftliche Mission zur...

Alle Focus-News des Innovations-reports >>>

Anzeige

Anzeige

IHR
JOB & KARRIERE
SERVICE
im innovations-report
in Kooperation mit academics
Veranstaltungen

Von Batterieforschung bis Optoelektronik

23.06.2017 | Veranstaltungen

10. HDT-Tagung: Elektrische Antriebstechnologie für Hybrid- und Elektrofahrzeuge

22.06.2017 | Veranstaltungen

„Fit für die Industrie 4.0“ – Tagung von Hochschule Darmstadt und Schader-Stiftung am 27. Juni

22.06.2017 | Veranstaltungen

 
VideoLinks
B2B-VideoLinks
Weitere VideoLinks >>>
Aktuelle Beiträge

Radioaktive Elemente in Cassiopeia A liefern Hinweise auf Neutrinos als Ursache der Supernova-Explosion

23.06.2017 | Physik Astronomie

Dünenökosysteme modellieren

23.06.2017 | Ökologie Umwelt- Naturschutz

Makro-Mikrowelle macht Leichtbau für Luft- und Raumfahrt effizienter

23.06.2017 | Materialwissenschaften