Forum für Wissenschaft, Industrie und Wirtschaft

Hauptsponsoren:     3M 
Datenbankrecherche:

 

Vitamin D deficiency linked to Type 1 diabetes

16.11.2012
A study led by researchers from the University of California, San Diego School of Medicine has found a correlation between vitamin D3 serum levels and subsequent incidence of Type 1 diabetes.

The six-year study of blood levels of nearly 2,000 individuals suggests a preventive role for vitamin D3 in this disease. The research appears the December issue of Diabetologia, a publication of the European Association for the Study of Diabetes (EASD).

"Previous studies proposed the existence of an association between vitamin D deficiency and risk of and Type 1 diabetes, but this is the first time that the theory has been tested in a way that provides the dose-response relationship," said Cedric Garland, DrPH, FACE, professor in UCSD's Department of Family and Preventive Medicine.

This study used samples from millions of blood serum specimens frozen by the Department of Defense Serum Registry for disease surveillance. The researchers thawed and analyzed 1000 samples of serum from healthy people who later developed type 1 diabetes and 1000 healthy controls whose blood was drawn on or near the same date but who did not develop type 1 diabetes. By comparing the serum concentrations of the predominant circulating form of vitamin D – 25-hydroxyvitamin D (25(OH)D) – investigators were able to determine the optimal serum level needed to lower an individual's risk of developing type 1 diabetes.

Based mainly on results of this study, Garland estimates that the level of 25(OH)D needed to prevent half the cases of type 1 diabetes is 50 ng/ml. A consensus of all available data indicates no known risk associated with this dosage.

"While there are a few conditions that influence vitamin D metabolism, for most people, 4000 IU per day of vitamin D3 will be needed to achieve the effective levels," Garland suggested. He urges interested patients to ask their health care provider to measure their serum 25(OH)D before increasing vitamin D3 intake.

"This beneficial effect is present at these intakes only for vitamin D3," cautioned Garland. "Reliance should not be placed on different forms of vitamin D and mega doses should be avoided, as most of the benefits for prevention of disease are for doses less than 10,000 IU/day."

Garland's co-authors from UC San Diego School of Medicine and the Naval Health Research Center include Edward Gorham, PhD; Sharif Mohr, PhD; and Heather Hofflich, DO; Alina Burgi and Kenneth Zeng of the Naval Health Research Center, and Camillo Ricordi MD, of the University of Miami Diabetes Research Institute.

The study was supported by a Congressional allocation to the Diabetes Research Institute of the University of Miami through the Naval Health Research Center, San Diego, California.

Kim Edwards | EurekAlert!
Further information:
http://www.ucsd.edu

More articles from Health and Medicine:

nachricht Using DNA origami to build nanodevices of the future
31.08.2015 | Institute for Integrated Cell-Material Sciences at Kyoto University

nachricht An ounce of prevention: Research advances on 'scourge' of transplant wards
28.08.2015 | University of Wisconsin-Madison

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Universum: Simulationen am Supercomputer

Davon träumt die Wissenschaft: An einem Computer zu simulieren, wie sich das Universum bis heute entwickelt hat. Forscher aus Würzburg und Heidelberg wollen dem Traum jetzt näher kommen: Sie haben Rechenzeit im Wert von knapp fünf Millionen Euro auf einem Supercomputer bewilligt bekommen.

Der Würzburger Mathematiker Professor Christian Klingenberg und der Heidelberger Astrophysiker Professor Volker Springel haben sich Großes vorgenommen: Sie...

Im Focus: An engineered surface unsticks sticky water droplets

The leaves of the lotus flower, and other natural surfaces that repel water and dirt, have been the model for many types of engineered liquid-repelling surfaces. As slippery as these surfaces are, however, tiny water droplets still stick to them. Now, Penn State researchers have developed nano/micro-textured, highly slippery surfaces able to outperform these naturally inspired coatings, particularly when the water is a vapor or tiny droplets.

Enhancing the mobility of liquid droplets on rough surfaces could improve condensation heat transfer for power-plant heat exchangers, create more efficient...

Im Focus: Starke, aber zeitlich begrenzte Temperaturabkühlungen unter der Lupe

Grosse Vulkanausbrüche schleudern beträchtliche Mengen an Schwefeldioxid in die Atmosphäre, die sich in Aerosole umwandeln, in der Stratosphäre verteilen, dort einen Teil der Sonneneinstrahlung blockieren und so die Erdoberfläche für einige Jahre abkühlen.

Ein internationales Forscherteam mit Berner Beteiligung hat nun dank der Kombination von Jahrringuntersuchungen an Bäumen und Klimamodellen einen Ansatz...

Im Focus: Elektrofahrzeuge kabellos laden und entladen

Über ein kabelloses Ladesystem können Elektroautos künftig nicht nur tanken, sondern die Energie ins Stromnetz zurückspeisen. Auf diese Weise helfen sie das Netz zu stabilisieren. Das kostengünstige Ladesystem erreicht hohe Wirkungsgrade – über den vollen Leistungsbereich von 400 Watt bis 3,6 Kilowatt. Die Abstände zwischen Auto und Ladespule können bis zu 20 Zentimeter be- tragen. Auf der Internationalen Automobil Ausstellung IAA in Frankfurt stellen Fraunhofer-Forscher den Prototyp vom 15. bis 18. September 2015 vor (Halle 4, Stand D33).

Es regnet in Strömen. Wer jetzt ein dickes unhandliches Kabel zwischen Elektrofahrzeug und Ladesäule einstecken muss, wird patschnass. Doch es nützt nichts,...

Im Focus: Increasingly severe disturbances weaken world's temperate forests

Longer, more severe, and hotter droughts and a myriad of other threats, including diseases and more extensive and severe wildfires, are threatening to transform some of the world's temperate forests, a new study published in Science has found. Without informed management, some forests could convert to shrublands or grasslands within the coming decades.

"While we have been trying to manage for resilience of 20th century conditions, we realize now that we must prepare for transformations and attempt to ease...

Alle Focus-News des Innovations-reports >>>

Anzeige

Anzeige

IHR
JOB & KARRIERE
SERVICE
im innovations-report
in Kooperation mit academics
Veranstaltungen

Technologietag „Laser-Plasma-Hybridtechnologie“

01.09.2015 | Veranstaltungen

Kongress - Das Lebensende planen

01.09.2015 | Veranstaltungen

Internationale Ökologenkonferenz zeigt Wege in eine nachhaltige Zukunft auf

01.09.2015 | Veranstaltungen

 
B2B-VideoLinks
Weitere VideoLinks >>>
Aktuelle Beiträge

moove goes Luxemburg: vitaliberty und DKV Luxembourg starten Partnerschaft für gesunde Unternehmen im Großherzogtum

01.09.2015 | Unternehmensmeldung

Ausbildungsstart bei Siemens - rund 160 Azubis im 1. Ausbildungsjahr an fünf mitteldeutschen Standorten

01.09.2015 | Unternehmensmeldung

Siemens verkauft 18 Industriegasturbinen nach Thailand

01.09.2015 | Unternehmensmeldung