Forum für Wissenschaft, Industrie und Wirtschaft

Hauptsponsoren:     3M 
Datenbankrecherche:

 

Proven At Last - Alcohol Consumption Increases Increases Risk Of Gout

15.04.2004


The first large epidemiological study to assess the age-old belief that alcohol consumption increases the risk of gout is published in this week’s issue of THE LANCET. A prospective study of nearly 50,000 men showed that beer drinking was more likely to be associated with gout than spirits; whereas moderate wine consumption was not linked to a risk of the disease.



Alcohol consumption causes hyperuricaemia (increased production of uric acid) which when deposited in joints leads to gout. The association between alcohol consumption and risk of gout has been suspected since ancient times, but has not been prospectively confirmed. Additionally, potential differences in risk of gout posed by different alcoholic beverages have not been assessed.

Hyon K Choi from Massachusetts General Hospital, USA, and colleagues prospectively assessed alcohol consumption and incidence of gout among 47000 male medical staff over a 12-year period. 730 cases of gout were confirmed throughout the study period. Alcohol consumption was assessed as the quantity consumed relative to the typical ethanol content of alcoholic drinks: 12•8 g for one can of beer, 11•0 g for a glass of wine, and 14•0 g for a shot of spirits.


Compared with people who did not drink, alcohol consumption was linked to gout risk, with higher overall consumption increasing this risk: around a 30% increased risk for daily alcohol consumption between 10 and 15g; around 50% increased risk for daily consumption between 15 and 30g; around a doubling of gout risk for consumption between 30 and 50g; and a 2•5 times increased risk for a daily alcohol consumption above 50g.

Beer consumption showed the strongest independent association with the risk of gout; consumption of spirits had a weaker association, while moderate wine consumption was not associated with increased gout risk.

Dr Choi comments: “We found differences in the risk of gout for the three alcoholic beverages. Two or more beers per day increased the risk of gout 2•5-fold compared with no beer intake, whereas the same frequency of spirits intake increased the risk by 1•6 times compared with no spirits intake. Correspondingly, beer increased the risk of gout per serving per day more than twice as much as did spirits even though alcohol content per serving was less for beer than spirits. Further, wine consumption of two 4-oz glasses or more per day was not associated with an increased risk of gout.

These findings suggest that certain non-alcoholic components that vary across these alcoholic beverages play an important role in the incidence of gout. One candidate for this non-alcoholic component is the variation in purine contents among the individual alcoholic beverages. Beer is the only alcoholic beverage acknowledged to have a large purine content…Thus, the effect of ingested purine in beer on uric acid in blood might be sufficient to augment the hyperuricaemic effect of alcohol itself producing a greater risk of gout than spirits or wine. Whether there might be other non-alcoholic risk factors in beer, or protective factors in wine, remains unknown”.

See Commentary (p xxx) available Thursday 15th April.

Contact: Dr Hyon K Choi, Arthritis Unit, Bulfinch 165, Massachusetts General Hospital, Fruit Street Boston, MA 02114, USA, Fone: +1 617 726 2870, Fax: +1 617 726 2872, Email: hchoi@partners.org

Richard Lane | alfa

Weitere Nachrichten aus der Kategorie Medizin Gesundheit:

nachricht Berner Forschende entdecken Schlaf-Wach-Schaltzentrale im Hirn
11.06.2018 | Universität Bern

nachricht Malaria: Kooperierende Antikörper verbessern Immunreaktion
08.06.2018 | Deutsches Krebsforschungszentrum

Alle Nachrichten aus der Kategorie: Medizin Gesundheit >>>

Die aktuellsten Pressemeldungen zum Suchbegriff Innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: AchemAsia 2019 in Shanghai

Die AchemAsia geht in ihr viertes Jahrzehnt und bricht auf zu neuen Ufern: Das International Expo and Innovation Forum for Sustainable Chemical Production findet vom 21. bis 23. Mai 2019 in Shanghai, China statt. Gleichzeitig erhält die Veranstaltung ein aktuelles Profil: Die elfte Ausgabe fokussiert auf Themen, die für Chinas Prozessindustrie besonders relevant sind, und legt den Schwerpunkt auf Nachhaltigkeit und Innovation.

1989 wurde die AchemAsia als Spin-Off der ACHEMA ins Leben gerufen, um die Bedürfnisse der sich damals noch entwickelnden Iindustrie in China zu erfüllen. Seit...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: Li-Fi erstmals für das industrielle Internet der Dinge getestet

Mit einer Abschlusspräsentation im BMW Werk München wurde das BMBF-geförderte Projekt OWICELLS erfolgreich abgeschlossen. Dabei wurde eine Li-Fi Kommunikation zu einem mobilen Roboter in einer 5x5m² Fertigungszelle demonstriert, der produktionsübliche Vorgänge durchführt (Teile schweißen, umlegen und prüfen). Die robuste, optische Drahtlosübertragung beruht auf räumlicher Diversität, d.h. Daten werden von mehreren LEDs und mehreren Photodioden gleichzeitig gesendet und empfangen. Das System kann Daten mit mehr als 100 Mbit/s und fünf Millisekunden Latenz übertragen.

Moderne Produktionstechniken in der Automobilindustrie müssen flexibler werden, um sich an individuelle Kundenwünsche anpassen zu können. Forscher untersuchen...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: ALMA entdeckt Trio von Baby-Planeten rund um neugeborenen Stern

Neuartige Technik, um die jüngsten Planeten in unserer Galaxis zu finden

Zwei unabhängige Astronomenteams haben mit ALMA überzeugende Belege dafür gefunden, dass sich drei junge Planeten im Orbit um den Säuglingsstern HD 163296...

Alle Focus-News des Innovations-reports >>>

Anzeige

Anzeige

VideoLinks
Industrie & Wirtschaft
Veranstaltungen

Künstliche Intelligenz – Schafft der Mensch seine Arbeit ab?

15.06.2018 | Veranstaltungen

Internationale Konferenz zur Asteroidenforschung in Garching

13.06.2018 | Veranstaltungen

Meteoriteneinschläge und Spektralfarben: HITS bei Explore Science 2018

11.06.2018 | Veranstaltungen

VideoLinks
Wissenschaft & Forschung
Weitere VideoLinks im Überblick >>>
 
Aktuelle Beiträge

EMAG auf der AMB: Hochproduktive Lösungen für die vernetzte Automotive-Produktion

15.06.2018 | Messenachrichten

AchemAsia 2019 in Shanghai

15.06.2018 | Messenachrichten

Dem Fettfinger zu Leibe rücken: Neuer Nanolack soll Antifingerprint-Oberflächen schaffen

15.06.2018 | Materialwissenschaften

Weitere B2B-VideoLinks
IHR
JOB & KARRIERE
SERVICE
im innovations-report
in Kooperation mit academics