Forum für Wissenschaft, Industrie und Wirtschaft

Hauptsponsoren:     3M 
Datenbankrecherche:

 

Stereoscopic mammography could reduce recall rate

13.11.2012
A new three-dimensional (3-D) digital mammography technique has the potential to significantly improve the accuracy of breast cancer screening, according to a study published in Radiology.

Two-dimensional (2-D) x-ray mammography, the current primary screening method for early detection of breast cancer in women, is a valuable tool but has some limitations. Surrounding normal tissue can mask lesions, and 2-D views do not provide direct information about the volumetric appearance—meaning the three-dimensional physical shape—of a detected lesion.

A novel technique called stereoscopic digital mammography (SDM) addresses these limitations by mimicking the way that human eyes work together to form a 3-D image. The technique uses digital mammography equipment that's been modified to allow the X-ray tube to move separately from the cassette. The resulting images are viewed on two monitors mounted one above the other.

"Our eyes see the world from two slightly different perspectives," said Carl J. D'Orsi, M.D., from the Department of Radiology and Imaging Sciences at Emory University School of Medicine and the Winship Cancer Institute at Emory University, both in Atlanta. "In this technique, the X-ray tube functions as the eyeball, with two different images providing slightly different views of the internal structure of the breast."

By using a unique workstation and polarizing lenses, SDM has the ability to identify lesions at different depths within the breast volume, potentially reducing both false positive findings and recalls while enabling more accurate diagnosis.

Dr. D'Orsi and colleagues recently compared SDM to 2-D digital mammography in 779 patients at elevated risk of developing breast cancer because of personal or family history. Patients received both exams in a single visit, and two experienced radiologists independently interpreted the final total of 1,298 exams. Imaging findings were correlated with results of one-year follow up or biopsy.

SDM significantly improved the accuracy of cancer detection. The specificity of 91.2 percent was better than the 87.8 percent rate for 2-D digital mammography; and the accuracy of 90.9 percent, compared with 87.4 percent for 2-D digital mammography, was also a statistically significant improvement.

"We found that the stereoscopic technique could significantly decrease the need for calling women back for additional exams," Dr. D'Orsi said.

Dr. D'Orsi and colleagues are expanding their research to study

SDM with a lower radiation dose in the general screening population. The radiation dose used in the study was approximately double the standard dose for mammography.

"In this study, we used a high-risk population to get an adequate number of cancers, and we acquired each of the images comprising the stereo pairs with a full standard X-ray dose," he said. "Now that we know the technique is worthwhile, we're repeating the study in the general population with a dose comparable to routine screening mammography."

"Stereoscopic Digital Mammography: Improved Specificity and Reduced Rate of Recall in a Prospective Clinical Trial." Collaborating with Dr. D'Orsi were David J. Getty, Ph.D., Ronald M. Pickett, Ph.D., Ioannis Sechopoulos, Ph.D., Mary S. Newell, M.D., Kathleen R. Gundry, M.D., Sandra R. Bates, M.D., Robert M. Nishikawa, Ph.D., Edward A. Sickles, M.D., Andrew Karellas, Ph.D., and Ellen M. D'Orsi, R.T. (R)(M).

Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc. (http://radiology.rsna.org/)

RSNA is an association of more than 50,000 radiologists, radiation oncologists, medical physicists and related scientists, promoting excellence in patient care and health care delivery through education, research and technologic innovation.

The Society is based in Oak Brook, Ill. (RSNA.org)

For patient-friendly information on breast imaging, visit RadiologyInfo.org.

Linda Brooks | EurekAlert!
Further information:
http://www.rsna.org

More articles from Medical Engineering:

nachricht Termination of lethal arrhythmia with light
13.09.2016 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Sensor systems identify senior citizens at risk of falling within 3 weeks
29.08.2016 | University of Missouri-Columbia

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Synthese-chemischer Meilenstein: Neues Ferrocenium-Molekül entdeckt

Wissenschaftler der Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) haben zusammen mit Kollegen der Freien Universität Berlin ein neues Molekül entdeckt: Die Eisenverbindung in der seltenen Oxidationsstufe +4 gehört zu den Ferrocenen und ist äußerst schwierig zu synthetisieren.

Metallocene werden umgangssprachlich auch als Sandwichverbindungen bezeichnet. Sie bestehen aus zwei organischen ringförmigen Verbindungen, den...

Im Focus: Neue Entwicklungen in der Asphären-Messtechnik

Kompetenzzentrum Ultrapräzise Oberflächenbearbeitung (CC UPOB) lädt zum Expertentreffen im März 2017 ein

Ob in Weltraumteleskopen, deren Optiken trotz großer Abmessungen nanometergenau gefertigt sein müssen, in Handykameras oder in Endoskopen − Asphären kommen in...

Im Focus: Mit OLED Mikrodisplays in Datenbrillen zur verbesserten Mensch-Maschine-Interaktion

Das Fraunhofer-Institut für Organische Elektronik, Elektronenstrahl- und Plasmatechnik FEP arbeitet seit Jahren an verschiedenen Entwicklungen zu OLED-Mikrodisplays, die auf organischen Halbleitern basieren. Durch die Integration einer Bildsensorfunktion direkt im Mikrodisplay, lässt sich u.a. die Augenbewegung in Datenbrillen aufnehmen und zur Steuerung von Display-Inhalten nutzen. Das verbesserte Konzept wird erstmals auf der Augmented World Expo Europe (AWE), vom 18. – 19. Oktober 2016, in Berlin, Stand B25 vorgestellt.

„Augmented Reality“ (erweiterte Realität) und „Wearable Displays“ (tragbare Displays) sind Schlagworte, denen man mittlerweile fast täglich begegnet. Beide...

Im Focus: OLED microdisplays in data glasses for improved human-machine interaction

The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.

“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...

Im Focus: Künstliche Intelligenz ermöglicht die Entdeckung neuer Materialien

Mit Methoden der künstlichen Intelligenz haben Chemiker der Universität Basel die Eigenschaften von rund 2 Millionen Kristallen berechnet, die aus vier verschiedenen chemischen Elementen zusammengesetzt sind. Dabei konnten die Forscher 90 bisher unbekannte Kristalle identifizieren, die thermodynamisch stabil sind und als neuartige Werkstoffe in Betracht kommen. Das berichten sie in der Fachzeitschrift «Physical Review Letters».

Elpasolith ist ein glasiges, transparentes, glänzendes und weiches Mineral mit kubischer Kristallstruktur. Erstmals entdeckt im El Paso County (USA), kann man...

Alle Focus-News des Innovations-reports >>>

Anzeige

Anzeige

IHR
JOB & KARRIERE
SERVICE
im innovations-report
in Kooperation mit academics
Veranstaltungen

Einsteins Geburtsstadt wird für eine Woche Hauptstadt der Physik

23.09.2016 | Veranstaltungen

Industrie und Wissenschaft diskutieren künftigen Mobilfunk-Standard 5G auf Tagung in Kassel

23.09.2016 | Veranstaltungen

Fachgespräch Feste Biomasse diskutiert Fragen zum Thema "Qualitätshackschnitzel"

23.09.2016 | Veranstaltungen

 
B2B-VideoLinks
Weitere VideoLinks >>>
Aktuelle Beiträge

Das Korallenthermometer muss neu justiert werden

23.09.2016 | Biowissenschaften Chemie

Doppel-Infektion macht Erreger aggressiver

23.09.2016 | Biowissenschaften Chemie

Synthese-chemischer Meilenstein: Neues Ferrocenium-Molekül entdeckt

23.09.2016 | Biowissenschaften Chemie